Perricone MD Cold Plasma Face & Eyes



Dr. Perricone originally began his walk to fame with his book ‘The Wrinkle Cure’. He has been in media quite a bit lately, and has a whole line of products. His Cold Plasma is one of his best-selling products. It is advertised as his most comprehensive and efficacious one to date, and it has won a number of awards.

Marie Claire listed it as one of 25 products that can change your life, and QVC gave it its Q-star award.

Cold Plasma is formulated to address 10 of the most visible signs of aging:

  • Redness
  • Loss of radiance
  • Discoloration
  • Enlarged pores
  • Uneven skin tone
  • Wrinkles
  • Dryness
  • Loss of firmness
  • Loss of smoothness
  • Impurities

Overall, it has a good ingredient list. It was developed over five years, with physicists at Los Alamos Laboratories.

Main ingredients include:

Neuro-peptides – to help with the ten signs of aging

DMAE – to lift and firm sagging skin

L-tyrosine – to brighten the skin

DHA – to hydrate the skin

However, even though it does contain many good ingredients, the jar packaging exposes them to light and air, which unfortunately makes many of the ingredients unstable once opened.

Cold Plasma is fragrance-free, which is important in a skin care product. However, for some strange reason, the eye cream contains fragrance chemicals like linalool and farnesol, which can cause irritation and actually reduce collagen production.

Our research into some questions people often ask:

What exactly is Cold Plasma? Cold plasma is an ionized gas that has low energy. We have not been able to determine what this has to do with skincare, but it is a unique angle to this product line.

Cold Plasma also claims to work with an Ionic-Suspension Carrier. Ions are atoms that have lost or gained electrons, making them positively or negatively charged. While other creams do contain ions that are suspended, we haven’t seen this scientific terminology used with other creams before, and have not been able to conclusively determine whether there is anything different about this or not.

The only other main issue we could find with Cold Plasma is that it has a fishy smell. If you can tolerate that though, Cold Plasma does seem to work well for many people, of all ages and all skin types. It’s not greasy and it absorbs quickly, and makes a great base for makeup.


The face cream retails at $150 an ounce, and the eye cream retails at $95 for half an ounce. You can buy them together for $195, a $50 savings.

Money back guarantee:

Cold Plasma comes with a 45-day money back guarantee.


They offer free shipping on the main website.

Replenishment program:

They have an auto-ship program where you can automatically receive a replenishment every 60 days.

Ingredient list for face cream:

Water, Glycerin, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Isopropyl Palmitate, L-Tyrosine, Butylene Glycol, Glyceryl Stearate, Peg-100 Stearate, Cetearyl Alcohol, Oligopeptide-17, Ceteareth-20, Magnesium Aspartate, Zinc Gluconate, Dimethyl Mea (Dmae), Docosahexaenoic Acid, Ascorbyl Palmitate, Phenoxyethanol, Dimethicone, Caprylyl Glycol, Glycolic Acid, Retinyl Palmitate, Saccaromyces Ferment, Elaeis Guineensis (Palm) Oil, Carbomer, Disodium Edta, Tocotrienols, Copper Gluconate, Polysorbate 20, Sorbic Acid, Tocopherol, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Oligopeptide, Astaxanthin, Palmitoyl Tetrapeptide-3

Ingredient list for eye cream:

Water, Cetearyl Alcohol, Phosphatidylcholine, Isopropyl Palmitate, Glycerin, Tetrahexyldecyl Ascorbate, Glyceryl Stearate, Peg-100 Stearate, Docosahexaenoic Acid, Squalane, Butylene Glycol, Benzyl Alcohol, Ceteareth-20, Magnesium Aspartate, Zinc Gluconate, Olea Europaea (Olive) Fruit Oil, Hydrogenated Vegetable Oil, Disodium Edta, Farnesol, Oligopeptide-17, Elaris Guineensis (Palm) Oil, Carbomer, Copper Gluconate, Tocotrienols, Polysorbate 20, Tocopherol, Sodium Hyaluronate, Fragrance, Linalool, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7

Editors' Rating: 7.3
Average Customer Rating
Rating: 4.8/5 (546 votes cast)
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* Comments on Skincare Search are genuine. As with all skincare products, results vary by consumer.

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